Beam Therapeutics

Senior Scientist/Principal Scientist, Data Science & Bioinformatics

19 March 2024
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Deadline date:
£116000 - £227000

Job Description

Position Overview

We are seeking an innovative, collaborative, and accomplished bioinformatics scientist to guide the development of novel therapies using our next-generation gene editing technologies. The individual in this role work closely with teams throughout Beam’s R&D organization to design new data-driven solutions and to better understand and optimize our gene editing technologies and delivery platforms.

Primary Responsibilities:

  • Lead the development and strategic deployment of custom machine learning models leveraging our extensive internal data stores.
  • Spearhead large-scale data analysis initiatives to accelerate LNP development.
  • Integrate bioinformatics, genomics, and functional data, generating new insights into base editor behavior.
  • Design and implement custom bioinformatics data pipelines to analyze results from novel and established next-generation sequencing (NGS) assays.
  • Collaborate with our Lead Discovery, Lead Optimization, and LNP teams to design data-driven solutions across our technology platform.
  • Communicate scientifically rigorous findings via verbal and written communications, visualizations, and presentations.

Qualifications:

  • A Ph.D. or equivalent experience in Bioinformatics, Structural Biology, Biophysics, or another relevant field
  • 5+ years of related experience in an industry setting strongly preferred
  • Strong scientific background, including an understanding of gene editing, molecular biology, structural biology, and statistics
  • Experience working with multiple sequence alignments and large sequence datasets
  • Proficiency with common bioinformatics tools for NGS data analysis and working with “omics” datasets
  • Demonstrated expertise in Python and data science software tools
  • Ability to work both independently and collaboratively on scientific challenges